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SKIN ENCYCLOPEDIA

PDRN and PN

August 15, 2026

Injectables

PDRN·PN

DNA-derived substances extracted and purified from sources such as salmon, dealt with in research related to skin regeneration.

What the term refers to

PDRN stands for polydeoxyribonucleotide and PN for polynucleotide, and they differ in molecular size and method of purification. They are used by injecting them into the skin in injectable form.

Good to know

The purpose of use differs by product and concentration. There may be pain on injection or a temporary sensation of small nodules, so it is best to follow the after-care guidance.

This entry is general medical information provided to aid understanding. It does not guarantee the results of any specific treatment or product, and diagnostic and treatment methods and their outcomes may differ depending on each person's condition. Please confirm the details through a medical consultation.

Director Kim Hyun-joo
Kim Hyun-jooDirector of Mason Clinic · Medical content author/reviewer

Graduate of Kyung Hee University School of Medicine (Magna cum laude) · Former director of Plus Hu Clinic, Girin Plastic Surgery, and DA Plastic Surgery · Regular member of the Korean Academy of Filler, Korean Academy of Aesthetic Plastic & Laser Medicine, Korean Academy of Laser, Dermatology and Trichology (KALDAT), Korean Lifting Research Society (KAFC), Korean Association of Obesity Research Physicians, and Korean Society for the Study of Obesity · Thermage User Training Course certified expert

The medical information on this page was written and reviewed by the director of Mason Clinic. Treatment results may vary from person to person. · Last reviewed 2026-08-15